After Iowa jumped out to an early 3-0 lead, the Aces would chip away, scoring single runs in the first, second and fourth innings. Sacrifice flies by Andy Tracy and Evan Frey in the first two frames cut the lead to 3-2 before Frey tied the game at three with an RBI single in the fourth.
But the I-Cubs broke the tie in the seventh, putting up six runs against three Aces pitchers. Reno scored two runs in the bottom of the seventh and threatened in the eighth, but left runners on second and third and could not complete the comeback.
Kevin Mulvey (2-3) took the loss for Reno, as he was tagged for five earned runs in 6 1-3 innings, striking out one and walking three.
I-Cubs starter Austin Bibens-Dirkx (3-1) earned the victory, scattering 10 hits over six frames but allowing just two earned runs. Justin Berg threw a scoreless ninth to pick up his first save of the season.
Tony Abreu led Reno with three hits while driving in two runs. Frey finished 1-for-3 with a walk and three RBIs. Sean Burroughs and Cody Ransom chipped in with two hits apiece.
Reno and Iowa conclude the series Tuesday morning at Aces Ballpark. The Aces will send RHP Barry Enright (0-1, 5.40 ERA) to the hill against Cubs RHP Jay Jackson (1-1, 5.31 ERA). First pitch is set for11:35 a.m. PT and is Education Day.